VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

Stock Comparison

WuXi AppTec Co., Ltd. vs Thermo Fisher Scientific Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

WuXi AppTec Co., Ltd.

603259 · Shanghai Stock Exchange

Market cap (USD)$37.4B
Gross margin (TTM)49.2%
Operating margin (TTM)42.7%
Net margin (TTM)41.7%
SectorHealthcare
IndustryMedical - Diagnostics & Research
CountryCN
Data as of2026-05-01
Moat score
72/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into WuXi AppTec Co., Ltd.'s moat claims, evidence, and risks.

View 603259 analysis

Thermo Fisher Scientific Inc.

TMO · New York Stock Exchange

Market cap (USD)$168.7B
Gross margin (TTM)39.4%
Operating margin (TTM)17.8%
Net margin (TTM)15.2%
SectorHealthcare
IndustryMedical - Diagnostics & Research
CountryUS
Data as of2025-12-22
Moat score
64/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Thermo Fisher Scientific Inc.'s moat claims, evidence, and risks.

View TMO analysis

Comparison highlights

  • Moat score gap: WuXi AppTec Co., Ltd. leads (72 / 100 vs 64 / 100 for Thermo Fisher Scientific Inc.).
  • Segment focus: WuXi AppTec Co., Ltd. has 3 segments (84% in WuXi Chemistry); Thermo Fisher Scientific Inc. has 4 segments (53.6% in Laboratory Products and Biopharma Services).
  • Moat breadth: WuXi AppTec Co., Ltd. has 5 moat types across 3 domains; Thermo Fisher Scientific Inc. has 8 across 3.

Primary market context

WuXi AppTec Co., Ltd.

WuXi Chemistry

Market

Global synthetic-molecule CRDMO services, including small-molecule discovery, process development, API manufacturing, peptides and oligonucleotides

Geography

Global, with major customer exposure to the United States, Europe and China

Customer

Large pharmaceutical companies, emerging biotechs and virtual pharma companies

Role

Integrated contract research, development and manufacturing partner across discovery, development and commercial manufacturing

Revenue share

84%

Thermo Fisher Scientific Inc.

Laboratory Products and Biopharma Services

Market

Laboratory supplies distribution/market channel plus outsourced biopharma services (CDMO/CRO)

Geography

Global

Customer

Pharma & biotech; academic/government labs; industrial and clinical laboratories

Role

Distributor/market channel and outsourced services provider

Revenue share

53.6%

Side-by-side metrics

WuXi AppTec Co., Ltd.
Thermo Fisher Scientific Inc.
Ticker / Exchange
603259 - Shanghai Stock Exchange
TMO - New York Stock Exchange
Market cap (USD)
$37.4B
$168.7B
Gross margin (TTM)
49.2%
39.4%
Operating margin (TTM)
42.7%
17.8%
Net margin (TTM)
41.7%
15.2%
Sector
Healthcare
Healthcare
Industry
Medical - Diagnostics & Research
Medical - Diagnostics & Research
HQ country
CN
US
Primary segment
WuXi Chemistry
Laboratory Products and Biopharma Services
Market structure
Competitive
Competitive
Market share
6%-9% (implied)
n/a
HHI estimate
n/a
n/a
Pricing power
Moderate
Moderate
Moat score
72 / 100
64 / 100
Moat domains
Supply, Demand, Legal
Demand, Supply, Legal
Last update
2026-05-01
2025-12-22

Moat coverage

Shared moat types

Capacity Moat

WuXi AppTec Co., Ltd. strengths

Scope EconomiesDesign In QualificationCompliance AdvantageOperational Excellence

Thermo Fisher Scientific Inc. strengths

Installed Base ConsumablesFormat Lock InBrand TrustService Field NetworkRegulated Standards PipeDistribution ControlProcurement Inertia

Segment mix

WuXi AppTec Co., Ltd. segments

Full profile >

WuXi Chemistry

Competitive

84%

WuXi Testing

Competitive

9.3%

WuXi Biology

Competitive

6.2%

Thermo Fisher Scientific Inc. segments

Full profile >

Life Sciences Solutions

Oligopoly

19%

Analytical Instruments

Oligopoly

17%

Specialty Diagnostics

Oligopoly

10.4%

Laboratory Products and Biopharma Services

Competitive

53.6%

Want the full wide moat stocks list?

Browse the full ranking of wide moat stocks, updated with moat scores and segment context.

View the moat stocks list

Looking for expansion-stage stocks?

Proven models entering the expansion stage with unit economics that work.

View expansion-stage stocks

Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.