WIDE MOAT STOCKS COMPARISON

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Stock Comparison

GSK plc vs Pfizer Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

GSK plc

GSK · London Stock Exchange

Market cap (USD)$100B
Gross margin (TTM)73.3%
Operating margin (TTM)24.1%
Net margin (TTM)14.5%
SectorHealthcare
IndustryDrug Manufacturers - General
CountryGB
Data as of2026-08-23
Moat score
57/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into GSK plc's moat claims, evidence, and risks.

View GSK analysis

Pfizer Inc.

PFE · New York Stock Exchange

Market cap (USD)$162.1B
Gross margin (TTM)71.3%
Operating margin (TTM)25.1%
Net margin (TTM)6.8%
SectorHealthcare
IndustryDrug Manufacturers - General
CountryUS
Data as of2026-08-23
Moat score
58/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Pfizer Inc.'s moat claims, evidence, and risks.

View PFE analysis

Comparison highlights

  • Moat score gap: Pfizer Inc. leads (58 / 100 vs 57 / 100 for GSK plc).
  • Segment focus: GSK plc has 3 segments (43.7% in Specialty Medicines); Pfizer Inc. has 5 segments (37.5% in Primary Care).
  • Primary market structure: Competitive vs Oligopoly. Pricing power: Moderate vs Moderate.
  • Moat breadth: GSK plc has 1 moat types across 1 domains; Pfizer Inc. has 1 across 1.

Primary market context

GSK plc

Specialty Medicines

Market

Branded specialty pharmaceuticals (HIV, oncology, immunology/respiratory)

Geography

Global

Customer

Hospitals, specialist physicians, payers

Role

Innovator & branded manufacturer

Revenue share

43.7%

Pfizer Inc.

Primary Care

Market

Branded primary care medicines and vaccines (incl. cardiovascular, migraine, pneumococcal/RSV/COVID-19)

Geography

Global

Customer

Healthcare providers, payers/PBMs, pharmacies/wholesalers, and government procurement

Role

Innovator biopharma (R&D + manufacturing + commercialization)

Revenue share

37.5%

Side-by-side metrics

GSK plc
Pfizer Inc.
Ticker / Exchange
GSK - London Stock Exchange
PFE - New York Stock Exchange
Market cap (USD)
$100B
$162.1B
Gross margin (TTM)
73.3%
71.3%
Operating margin (TTM)
24.1%
25.1%
Net margin (TTM)
14.5%
6.8%
Sector
Healthcare
Healthcare
Industry
Drug Manufacturers - General
Drug Manufacturers - General
HQ country
GB
US
Primary segment
Specialty Medicines
Primary Care
Market structure
Competitive
Oligopoly
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Moderate
Moderate
Moat score
57 / 100
58 / 100
Moat domains
Legal
Legal
Last update
2026-09-05
2026-09-05

Moat coverage

Shared moat types

IP Choke Point

GSK plc strengths

No unique moat types yet.

Pfizer Inc. strengths

No unique moat types yet.

Segment mix

GSK plc segments

Full profile >

Vaccines

Oligopoly

27.6%

Specialty Medicines

Competitive

43.7%

General Medicines

Competitive

28.7%

Pfizer Inc. segments

Full profile >

Primary Care

Oligopoly

37.5%

Specialty Care

Oligopoly

21.3%

Oncology

Competitive

27.1%

Hospital and Biosimilars

Competitive

11.9%

Pfizer CentreOne

Competitive

2.2%

Act on this comparison

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.