WIDE MOAT STOCKS COMPARISON

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Stock Comparison

Novartis AG vs Roche Holding AG

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

Novartis AG

NOVN · SIX Swiss Exchange

Market cap (USD)$272B
Gross margin (TTM)74.7%
Operating margin (TTM)30.2%
Net margin (TTM)22.5%
SectorHealthcare
IndustryPharmaceuticals
CountryCH
Data as of2026-08-23
56/100
Moat score

Weighted across the company's segments.

Full stock profile

Dive deeper into Novartis AG's moat claims, evidence, and risks.

View NOVN analysis

Roche Holding AG

ROP · SIX Swiss Exchange (participation certificate)

Market cap (USD)$334.5B
Gross margin (TTM)72.7%
Operating margin (TTM)29.2%
Net margin (TTM)20.3%
SectorHealthcare
IndustryPharmaceuticals
CountryCH
Data as of2026-08-23
69/100
Moat score

Weighted across the company's segments.

Full stock profile

Dive deeper into Roche Holding AG's moat claims, evidence, and risks.

View ROP analysis

Comparison highlights

  • Moat score gap: Roche Holding AG leads (69 / 100 vs 56 / 100 for Novartis AG).
  • Segment focus: Novartis AG has 5 segments (31% in Oncology); Roche Holding AG has 2 segments (77.8% in Pharmaceuticals).
  • Primary market structure: Oligopoly vs Competitive. Pricing power: Moderate vs Moderate.
  • Moat breadth: Novartis AG has 2 moat types across 2 domains; Roche Holding AG has 3 across 2.

Primary market context

Novartis AG

Oncology

Market

Oncology and hematology branded medicines (including targeted therapies and radioligand therapy)

Geography

Global

Customer

Oncologists and hospitals; reimbursed by payers; hospital and specialty pharmacy channels

Role

Originator developer, manufacturer, and marketer of oncology therapies

Revenue share

31%

Roche Holding AG

Pharmaceuticals

Market

Innovative (branded) prescription pharmaceuticals

Geography

Global

Customer

Healthcare providers and systems (hospitals/clinics), payers/governments, and patients

Role

Innovator pharmaceutical developer, manufacturer and marketer

Revenue share

77.8%

Side-by-side metrics

Novartis AG
Roche Holding AG
Ticker / Exchange
NOVN - SIX Swiss Exchange
ROP - SIX Swiss Exchange (participation certificate)
Market cap (USD)
$272B
$334.5B
Gross margin (TTM)
74.7%
72.7%
Operating margin (TTM)
30.2%
29.2%
Net margin (TTM)
22.5%
20.3%
Sector
Healthcare
Healthcare
Industry
Pharmaceuticals
Pharmaceuticals
HQ country
CH
CH
Primary segment
Oncology
Pharmaceuticals
Market structure
Oligopoly
Competitive
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Moderate
Moderate
Moat score
56 / 100
69 / 100
Moat domains
Legal, Supply
Legal, Demand
Last update
2026-09-05
2026-09-05

Moat coverage

Shared moat types

IP Choke Point

Novartis AG strengths

Capex Knowhow Scale

Roche Holding AG strengths

Installed Base ConsumablesData Workflow Lockin

Segment mix

Novartis AG segments

Full profile >

Cardiovascular, Renal and Metabolic

Oligopoly

12.6%

Immunology

Oligopoly

19.1%

Neuroscience

Oligopoly

12.5%

Oncology

Oligopoly

31%

Established Brands

Competitive

24.9%

Roche Holding AG segments

Full profile >

Pharmaceuticals

Competitive

77.8%

Diagnostics

Oligopoly

22.2%

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.