WIDE MOAT STOCKS COMPARISON

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Stock Comparison

Thermo Fisher Scientific Inc. vs Roche Holding AG

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

Thermo Fisher Scientific Inc.

TMO · New York Stock Exchange

Market cap (USD)$242.8B
Gross margin (TTM)40.8%
Operating margin (TTM)17.6%
Net margin (TTM)15%
SectorHealthcare
IndustryDiagnostics and life science tools
CountryUS
Data as of2026-08-23
59/100
Moat score

Weighted across the company's segments.

Full stock profile

Dive deeper into Thermo Fisher Scientific Inc.'s moat claims, evidence, and risks.

View TMO analysis

Roche Holding AG

ROP · SIX Swiss Exchange (participation certificate)

Market cap (USD)$334.5B
Gross margin (TTM)72.7%
Operating margin (TTM)29.2%
Net margin (TTM)20.3%
SectorHealthcare
IndustryPharmaceuticals
CountryCH
Data as of2026-08-23
69/100
Moat score

Weighted across the company's segments.

Full stock profile

Dive deeper into Roche Holding AG's moat claims, evidence, and risks.

View ROP analysis

Comparison highlights

  • Moat score gap: Roche Holding AG leads (69 / 100 vs 59 / 100 for Thermo Fisher Scientific Inc.).
  • Segment focus: Thermo Fisher Scientific Inc. has 4 segments (53.5% in Laboratory Products and Biopharma Services); Roche Holding AG has 2 segments (77.8% in Pharmaceuticals).
  • Moat breadth: Thermo Fisher Scientific Inc. has 3 moat types across 2 domains; Roche Holding AG has 3 across 2.

Primary market context

Thermo Fisher Scientific Inc.

Laboratory Products and Biopharma Services

Market

Laboratory supplies distribution/market channel plus outsourced biopharma services (CDMO/CRO)

Geography

Global

Customer

Pharma & biotech; academic/government labs; industrial and clinical laboratories

Role

Distributor/market channel and outsourced services provider

Revenue share

53.5%

Roche Holding AG

Pharmaceuticals

Market

Innovative (branded) prescription pharmaceuticals

Geography

Global

Customer

Healthcare providers and systems (hospitals/clinics), payers/governments, and patients

Role

Innovator pharmaceutical developer, manufacturer and marketer

Revenue share

77.8%

Side-by-side metrics

Thermo Fisher Scientific Inc.
Roche Holding AG
Ticker / Exchange
TMO - New York Stock Exchange
ROP - SIX Swiss Exchange (participation certificate)
Market cap (USD)
$242.8B
$334.5B
Gross margin (TTM)
40.8%
72.7%
Operating margin (TTM)
17.6%
29.2%
Net margin (TTM)
15%
20.3%
Sector
Healthcare
Healthcare
Industry
Diagnostics and life science tools
Pharmaceuticals
HQ country
US
CH
Primary segment
Laboratory Products and Biopharma Services
Pharmaceuticals
Market structure
Competitive
Competitive
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Moderate
Moderate
Moat score
59 / 100
69 / 100
Moat domains
Demand, Supply
Legal, Demand
Last update
2026-09-05
2026-09-05

Moat coverage

Shared moat types

Installed Base Consumables

Thermo Fisher Scientific Inc. strengths

Distribution ControlProcurement Inertia

Roche Holding AG strengths

IP Choke PointData Workflow Lockin

Segment mix

Thermo Fisher Scientific Inc. segments

Full profile >

Life Sciences Solutions

Oligopoly

19.7%

Analytical Instruments

Oligopoly

16.5%

Specialty Diagnostics

Oligopoly

10.3%

Laboratory Products and Biopharma Services

Competitive

53.5%

Roche Holding AG segments

Full profile >

Pharmaceuticals

Competitive

77.8%

Diagnostics

Oligopoly

22.2%

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.