VOL. XCIV, NO. 247

* WIDE MOAT STOCKS COMPARISON *

NO ADVICE

Sunday, December 28, 2025

Stock Comparison

GSK plc vs MarketAxess Holdings Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

GSK plc

GSK · London Stock Exchange

Market cap (USD)$98.8B
SectorHealthcare
CountryGB
Data as of2025-12-28
Moat score
62/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

View full moat analysis >

MarketAxess Holdings Inc.

MKTX · NASDAQ Global Select Market

Market cap (USD)$6.7B
SectorFinancials
CountryUS
Data as of2025-12-23
Moat score
74/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

View full moat analysis >

Side-by-side metrics

GSK plc
MarketAxess Holdings Inc.
Ticker / Exchange
GSK - London Stock Exchange
MKTX - NASDAQ Global Select Market
Market cap (USD)
$98.8B
$6.7B
Sector
Healthcare
Financials
HQ country
GB
US
Primary segment
Specialty Medicines
Trade Execution Solutions
Market structure
Oligopoly
Oligopoly
Market share
n/a
19% (reported)
HHI estimate
n/a
n/a
Pricing power
Strong
Moderate
Moat score
62 / 100
74 / 100
Moat domains
Supply, Legal, Demand
Network, Demand, Legal
Last update
2025-12-28
2025-12-23

Moat coverage

Shared moat types

Compliance AdvantageSwitching Costs General

GSK plc strengths

Capex Knowhow ScaleIP Choke Point

MarketAxess Holdings Inc. strengths

Two Sided NetworkData Workflow LockinData Network EffectsEcosystem Complements

Segment mix

GSK plc segments

Full profile >

Vaccines

Oligopoly

29.1%

Specialty Medicines

Oligopoly

37.6%

General Medicines

Competitive

33.2%

MarketAxess Holdings Inc. segments

Full profile >

Trade Execution Solutions

Oligopoly

87.1%

Services (Data, Post-Trade and Technology)

Competitive

12.9%

Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.