VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Stock Comparison

Danaher Corporation vs Thermo Fisher Scientific Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

Danaher Corporation

DHR · New York Stock Exchange

Market cap (USD)$153.1B
Gross margin (TTM)60.9%
Operating margin (TTM)20.9%
Net margin (TTM)14.7%
SectorHealthcare
IndustryMedical - Diagnostics & Research
CountryUS
Data as of2025-12-22
Moat score
77/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Danaher Corporation's moat claims, evidence, and risks.

View DHR analysis

Thermo Fisher Scientific Inc.

TMO · New York Stock Exchange

Market cap (USD)$203.9B
Gross margin (TTM)39.5%
Operating margin (TTM)18%
Net margin (TTM)15.1%
SectorHealthcare
IndustryMedical - Diagnostics & Research
CountryUS
Data as of2025-12-22
Moat score
64/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Thermo Fisher Scientific Inc.'s moat claims, evidence, and risks.

View TMO analysis

Comparison highlights

  • Moat score gap: Danaher Corporation leads (77 / 100 vs 64 / 100 for Thermo Fisher Scientific Inc.).
  • Segment focus: Danaher Corporation has 3 segments (41% in Diagnostics); Thermo Fisher Scientific Inc. has 4 segments (53.6% in Laboratory Products and Biopharma Services).
  • Primary market structure: Oligopoly vs Competitive. Pricing power: Moderate vs Moderate.
  • Moat breadth: Danaher Corporation has 7 moat types across 3 domains; Thermo Fisher Scientific Inc. has 8 across 3.

Primary market context

Danaher Corporation

Diagnostics

Market

In vitro diagnostics instruments, consumables, software and services (clinical lab, acute care/POC, pathology, molecular diagnostics)

Geography

Global

Customer

Hospitals, physician offices, reference laboratories, pathology labs, critical care settings

Role

IVD device manufacturer and reagent/test supplier + software/services

Revenue share

41%

Thermo Fisher Scientific Inc.

Laboratory Products and Biopharma Services

Market

Laboratory supplies distribution/market channel plus outsourced biopharma services (CDMO/CRO)

Geography

Global

Customer

Pharma & biotech; academic/government labs; industrial and clinical laboratories

Role

Distributor/market channel and outsourced services provider

Revenue share

53.6%

Side-by-side metrics

Danaher Corporation
Thermo Fisher Scientific Inc.
Ticker / Exchange
DHR - New York Stock Exchange
TMO - New York Stock Exchange
Market cap (USD)
$153.1B
$203.9B
Gross margin (TTM)
60.9%
39.5%
Operating margin (TTM)
20.9%
18%
Net margin (TTM)
14.7%
15.1%
Sector
Healthcare
Healthcare
Industry
Medical - Diagnostics & Research
Medical - Diagnostics & Research
HQ country
US
US
Primary segment
Diagnostics
Laboratory Products and Biopharma Services
Market structure
Oligopoly
Competitive
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Moderate
Moderate
Moat score
77 / 100
64 / 100
Moat domains
Demand, Supply, Legal
Demand, Supply, Legal
Last update
2025-12-22
2025-12-22

Moat coverage

Shared moat types

Installed Base ConsumablesService Field NetworkRegulated Standards Pipe

Danaher Corporation strengths

Design In QualificationOperational ExcellenceLearning Curve YieldSuite Bundling

Thermo Fisher Scientific Inc. strengths

Format Lock InBrand TrustDistribution ControlProcurement InertiaCapacity Moat

Segment mix

Danaher Corporation segments

Full profile >

Biotechnology

Oligopoly

28.3%

Life Sciences

Oligopoly

30.7%

Diagnostics

Oligopoly

41%

Thermo Fisher Scientific Inc. segments

Full profile >

Life Sciences Solutions

Oligopoly

19%

Analytical Instruments

Oligopoly

17%

Specialty Diagnostics

Oligopoly

10.4%

Laboratory Products and Biopharma Services

Competitive

53.6%

Want the full wide moat stocks list?

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Proven models entering the expansion stage with unit economics that work.

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.