VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Friday, January 2, 2026
Stock Comparison
AstraZeneca PLC vs MarketAxess Holdings Inc.
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
AstraZeneca PLC
AZN · London Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into AstraZeneca PLC's moat claims, evidence, and risks.
View AZN analysisMarketAxess Holdings Inc.
MKTX · NASDAQ Global Select Market
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into MarketAxess Holdings Inc.'s moat claims, evidence, and risks.
View MKTX analysisComparison highlights
- Moat score gap: MarketAxess Holdings Inc. leads (74 / 100 vs 71 / 100 for AstraZeneca PLC).
- Segment focus: AstraZeneca PLC has 6 segments (41% in Oncology); MarketAxess Holdings Inc. has 2 segments (87.1% in Trade Execution Solutions).
- Primary market structure: Oligopoly vs Oligopoly. Pricing power: Strong vs Moderate.
- Moat breadth: AstraZeneca PLC has 4 moat types across 3 domains; MarketAxess Holdings Inc. has 6 across 3.
Primary market context
AstraZeneca PLC
Oncology
Innovator oncology therapeutics (branded prescription medicines)
Global
Hospitals, oncology clinics, payers
Innovator biopharmaceutical company
41%
MarketAxess Holdings Inc.
Trade Execution Solutions
Electronic fixed-income trade execution platforms (credit and rates)
Global
Institutional investors, broker-dealers, and alternative liquidity providers
Electronic trading venue / marketplace operator
87.1%
Side-by-side metrics
Moat coverage
Shared moat types
No overlap yet.
AstraZeneca PLC strengths
MarketAxess Holdings Inc. strengths
Segment mix
AstraZeneca PLC segments
Full profile >Oncology
Oligopoly
Cardiovascular, Renal and Metabolism (CVRM)
Competitive
Respiratory & Immunology (R&I)
Oligopoly
Vaccines & Immune Therapies (V&I)
Oligopoly
Rare Disease
Oligopoly
Other Medicines
Competitive
MarketAxess Holdings Inc. segments
Full profile >Trade Execution Solutions
Oligopoly
Services (Data, Post-Trade and Technology)
Competitive
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View the moat stocks listCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.