VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

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Friday, January 2, 2026

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Stock Comparison

AstraZeneca PLC vs S&P Global Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

AstraZeneca PLC

AZN · London Stock Exchange

Market cap (USD)—

Gross margin (TTM)—

Operating margin (TTM)—

Net margin (TTM)—

SectorHealthcare

Industry—

CountryGB

Data as of2026-01-02

Moat score

71/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into AstraZeneca PLC's moat claims, evidence, and risks.

View AZN analysis

S&P Global Inc.

SPGI · New York Stock Exchange

Market cap (USD)$156.2B

Gross margin (TTM)70%

Operating margin (TTM)40.7%

Net margin (TTM)27.5%

SectorFinancials

IndustryFinancial - Data & Stock Exchanges

CountryUS

Data as of2025-12-21

Moat score

77/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into S&P Global Inc.'s moat claims, evidence, and risks.

View SPGI analysis

Comparison highlights

Moat score gap: S&P Global Inc. leads (77 / 100 vs 71 / 100 for AstraZeneca PLC).
Segment focus: AstraZeneca PLC has 6 segments (41% in Oncology); S&P Global Inc. has 5 segments (32.6% in S&P Global Market Intelligence).
Primary market structure: Oligopoly vs Oligopoly. Pricing power: Strong vs Moderate.
Moat breadth: AstraZeneca PLC has 4 moat types across 3 domains; S&P Global Inc. has 9 across 5.

Primary market context

AstraZeneca PLC

Oncology

Market

Innovator oncology therapeutics (branded prescription medicines)

Geography

Global

Customer

Hospitals, oncology clinics, payers

Role

Innovator biopharmaceutical company

Revenue share

41%

S&P Global Inc.

S&P Global Market Intelligence

Market

Financial market data, analytics, and workflow tools for institutions

Geography

Global

Customer

B2B (institutional investors, banks, insurers, corporates)

Role

Data/analytics and workflow software provider

Revenue share

32.6%

Side-by-side metrics

AstraZeneca PLC

S&P Global Inc.

Ticker / Exchange

AZN - London Stock Exchange

SPGI - New York Stock Exchange

Market cap (USD)

n/a

$156.2B

Gross margin (TTM)

n/a

70%

Operating margin (TTM)

n/a

40.7%

Net margin (TTM)

n/a

27.5%

Sector

Healthcare

Financials

Industry

n/a

Financial - Data & Stock Exchanges

HQ country

Primary segment

Oncology

S&P Global Market Intelligence

Market structure

Oligopoly

Market share

n/a

HHI estimate

n/a

Pricing power

Strong

Moderate

Moat score

71 / 100

77 / 100

Moat domains

Legal, Supply, Demand

Demand, Supply, Legal, Network, Financial

Last update

2026-01-02

2025-12-21

Moat coverage

Shared moat types

Regulated Standards PipeBrand Trust

AstraZeneca PLC strengths

IP Choke PointCapex Knowhow Scale

S&P Global Inc. strengths

Data Workflow LockinScope EconomiesDe Facto StandardCompliance AdvantageSwitching Costs GeneralEcosystem ComplementsBenchmark Pricing Power

Segment mix

AstraZeneca PLC segments

Full profile >

Oncology

Oligopoly

41%

Cardiovascular, Renal and Metabolism (CVRM)

Competitive

23%

Respiratory & Immunology (R&I)

Oligopoly

15%

Vaccines & Immune Therapies (V&I)

Oligopoly

Rare Disease

Oligopoly

16%

Other Medicines

Competitive

S&P Global Inc. segments

Full profile >

S&P Global Market Intelligence

Oligopoly

32.6%

S&P Global Ratings

Oligopoly

29.6%

S&P Global Commodity Insights

Oligopoly

15.1%

S&P Global Mobility

Competitive

11.3%

S&P Dow Jones Indices

Oligopoly

11.4%

Want the full wide moat stocks list?

Browse the full ranking of wide moat stocks, updated with moat scores and segment context.

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.