VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Tuesday, December 30, 2025
Stock Comparison
MarketAxess Holdings Inc. vs Pfizer Inc.
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
MarketAxess Holdings Inc.
MKTX · NASDAQ Global Select Market
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into MarketAxess Holdings Inc.'s moat claims, evidence, and risks.
View MKTX analysisPfizer Inc.
PFE · New York Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Comparison highlights
- Moat score gap: MarketAxess Holdings Inc. leads (74 / 100 vs 58 / 100 for Pfizer Inc.).
- Segment focus: MarketAxess Holdings Inc. has 2 segments (87.1% in Trade Execution Solutions); Pfizer Inc. has 5 segments (47.4% in Primary Care).
- Moat breadth: MarketAxess Holdings Inc. has 6 moat types across 3 domains; Pfizer Inc. has 8 across 3.
Primary market context
MarketAxess Holdings Inc.
Trade Execution Solutions
Electronic fixed-income trade execution platforms (credit and rates)
Global
Institutional investors, broker-dealers, and alternative liquidity providers
Electronic trading venue / marketplace operator
87.1%
Pfizer Inc.
Primary Care
Branded primary care medicines and vaccines (incl. cardiovascular, migraine, pneumococcal/RSV/COVID-19)
Global
Healthcare providers, payers/PBMs, pharmacies/wholesalers, and government procurement
Innovator biopharma (R&D + manufacturing + commercialization)
47.4%
Side-by-side metrics
Moat coverage
Shared moat types
MarketAxess Holdings Inc. strengths
Pfizer Inc. strengths
Segment mix
MarketAxess Holdings Inc. segments
Full profile >Trade Execution Solutions
Oligopoly
Services (Data, Post-Trade and Technology)
Competitive
Pfizer Inc. segments
Full profile >Primary Care
Oligopoly
Specialty Care
Oligopoly
Oncology
Competitive
Pfizer CentreOne
Competitive
Pfizer Ignite
Competitive
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View the moat stocks listCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.