VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Wednesday, December 31, 2025
Stock Comparison
Amgen Inc. vs O'Reilly Automotive, Inc.
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
Amgen Inc.
AMGN · Nasdaq Stock Market
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
O'Reilly Automotive, Inc.
ORLY · Nasdaq Global Select Market
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into O'Reilly Automotive, Inc.'s moat claims, evidence, and risks.
View ORLY analysisComparison highlights
- Moat score gap: Amgen Inc. leads (70 / 100 vs 63 / 100 for O'Reilly Automotive, Inc.).
- Segment focus: Amgen Inc. has 3 segments (80.1% in Core Innovative Medicines); O'Reilly Automotive, Inc. has 2 segments (52% in DIY Aftermarket Retail).
- Primary market structure: Competitive vs Oligopoly. Pricing power: Moderate vs Moderate.
- Moat breadth: Amgen Inc. has 5 moat types across 3 domains; O'Reilly Automotive, Inc. has 7 across 2.
Primary market context
Amgen Inc.
Core Innovative Medicines
Branded biopharmaceutical therapies for common diseases (bone health, inflammation, oncology, cardiovascular and other specialty areas)
Global
Payers, providers, and pharmacies
Drug developer/manufacturer
80.1%
O'Reilly Automotive, Inc.
DIY Aftermarket Retail
Specialty automotive aftermarket parts retail (DIY channel)
United States, Puerto Rico, Mexico, Canada
Consumers (do-it-yourself vehicle owners)
Specialty retailer
52%
Side-by-side metrics
Moat coverage
Shared moat types
Amgen Inc. strengths
O'Reilly Automotive, Inc. strengths
Segment mix
Amgen Inc. segments
Full profile >Core Innovative Medicines
Competitive
Rare Disease Portfolio (Horizon + others)
Quasi-Monopoly
Biosimilars
Oligopoly
O'Reilly Automotive, Inc. segments
Full profile >DIY Aftermarket Retail
Oligopoly
Professional (B2B) Aftermarket Distribution
Competitive
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View the moat stocks listCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.