VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Friday, January 2, 2026

Stock Comparison

ANSYS, Inc. vs AstraZeneca PLC

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

ANSYS, Inc.

ANSS · Nasdaq Global Select Market

Market cap (USD)$32.9B
Gross margin (TTM)88.8%
Operating margin (TTM)28.9%
Net margin (TTM)23%
SectorTechnology
IndustrySoftware - Application
CountryUS
Data as of2025-12-31
Moat score
68/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into ANSYS, Inc.'s moat claims, evidence, and risks.

View ANSS analysis

AstraZeneca PLC

AZN · London Stock Exchange

Market cap (USD)
Gross margin (TTM)
Operating margin (TTM)
Net margin (TTM)
SectorHealthcare
Industry
CountryGB
Data as of2026-01-02
Moat score
71/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into AstraZeneca PLC's moat claims, evidence, and risks.

View AZN analysis

Comparison highlights

  • Moat score gap: AstraZeneca PLC leads (71 / 100 vs 68 / 100 for ANSYS, Inc.).
  • Segment focus: ANSYS, Inc. has 3 segments; AstraZeneca PLC has 6 segments (41% in Oncology).
  • Primary market structure: Oligopoly vs Oligopoly. Pricing power: Moderate vs Strong.
  • Moat breadth: ANSYS, Inc. has 7 moat types across 3 domains; AstraZeneca PLC has 4 across 3.

Primary market context

ANSYS, Inc.

Core Multiphysics Simulation Platform (CAE)

Market

Multiphysics engineering simulation (CAE) software

Geography

Global

Customer

Enterprises and academia

Role

Engineering design, verification, and validation software

AstraZeneca PLC

Oncology

Market

Innovator oncology therapeutics (branded prescription medicines)

Geography

Global

Customer

Hospitals, oncology clinics, payers

Role

Innovator biopharmaceutical company

Revenue share

41%

Side-by-side metrics

ANSYS, Inc.
AstraZeneca PLC
Ticker / Exchange
ANSS - Nasdaq Global Select Market
AZN - London Stock Exchange
Market cap (USD)
$32.9B
n/a
Gross margin (TTM)
88.8%
n/a
Operating margin (TTM)
28.9%
n/a
Net margin (TTM)
23%
n/a
Sector
Technology
Healthcare
Industry
Software - Application
n/a
HQ country
US
GB
Primary segment
Core Multiphysics Simulation Platform (CAE)
Oncology
Market structure
Oligopoly
Oligopoly
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Moderate
Strong
Moat score
68 / 100
71 / 100
Moat domains
Demand, Network, Legal
Legal, Supply, Demand
Last update
2025-12-31
2026-01-02

Moat coverage

Shared moat types

No overlap yet.

ANSYS, Inc. strengths

Suite BundlingSwitching Costs GeneralData Workflow LockinDesign In QualificationDe Facto StandardEcosystem ComplementsCompliance Advantage

AstraZeneca PLC strengths

Regulated Standards PipeIP Choke PointCapex Knowhow ScaleBrand Trust

Segment mix

ANSYS, Inc. segments

Full profile >

Core Multiphysics Simulation Platform (CAE)

Oligopoly

n/a

Electronics & Semiconductor Simulation (EDA-adjacent)

Oligopoly

n/a

Digital Mission Engineering & Safety-Critical Tooling

Competitive

n/a

AstraZeneca PLC segments

Full profile >

Oncology

Oligopoly

41%

Cardiovascular, Renal and Metabolism (CVRM)

Competitive

23%

Respiratory & Immunology (R&I)

Oligopoly

15%

Vaccines & Immune Therapies (V&I)

Oligopoly

3%

Rare Disease

Oligopoly

16%

Other Medicines

Competitive

2%

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.