VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Wednesday, December 31, 2025

Stock Comparison

ANSYS, Inc. vs GSK plc

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

ANSYS, Inc.

ANSS · Nasdaq Global Select Market

Market cap (USD)
SectorTechnology
CountryUS
Data as of2025-12-31
Moat score
68/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into ANSYS, Inc.'s moat claims, evidence, and risks.

View ANSS analysis

GSK plc

GSK · London Stock Exchange

Market cap (USD)$98.8B
SectorHealthcare
CountryGB
Data as of2025-12-28
Moat score
62/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into GSK plc's moat claims, evidence, and risks.

View GSK analysis

Comparison highlights

  • Moat score gap: ANSYS, Inc. leads (68 / 100 vs 62 / 100 for GSK plc).
  • Segment focus: ANSYS, Inc. has 3 segments; GSK plc has 3 segments (37.6% in Specialty Medicines).
  • Primary market structure: Oligopoly vs Oligopoly. Pricing power: Moderate vs Strong.
  • Moat breadth: ANSYS, Inc. has 7 moat types across 3 domains; GSK plc has 4 across 3.

Primary market context

ANSYS, Inc.

Core Multiphysics Simulation Platform (CAE)

Market

Multiphysics engineering simulation (CAE) software

Geography

Global

Customer

Enterprises and academia

Role

Engineering design, verification, and validation software

GSK plc

Specialty Medicines

Market

Branded specialty pharmaceuticals (HIV, oncology, immunology/respiratory)

Geography

Global

Customer

Hospitals, specialist physicians, payers

Role

Innovator & branded manufacturer

Revenue share

37.6%

Side-by-side metrics

ANSYS, Inc.
GSK plc
Ticker / Exchange
ANSS - Nasdaq Global Select Market
GSK - London Stock Exchange
Market cap (USD)
n/a
$98.8B
Sector
Technology
Healthcare
HQ country
US
GB
Primary segment
Core Multiphysics Simulation Platform (CAE)
Specialty Medicines
Market structure
Oligopoly
Oligopoly
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Moderate
Strong
Moat score
68 / 100
62 / 100
Moat domains
Demand, Network, Legal
Supply, Legal, Demand
Last update
2025-12-31
2025-12-28

Moat coverage

Shared moat types

Switching Costs GeneralCompliance Advantage

ANSYS, Inc. strengths

Suite BundlingData Workflow LockinDesign In QualificationDe Facto StandardEcosystem Complements

GSK plc strengths

Capex Knowhow ScaleIP Choke Point

Segment mix

ANSYS, Inc. segments

Full profile >

Core Multiphysics Simulation Platform (CAE)

Oligopoly

n/a

Electronics & Semiconductor Simulation (EDA-adjacent)

Oligopoly

n/a

Digital Mission Engineering & Safety-Critical Tooling

Competitive

n/a

GSK plc segments

Full profile >

Vaccines

Oligopoly

29.1%

Specialty Medicines

Oligopoly

37.6%

General Medicines

Competitive

33.2%

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.