VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Friday, January 2, 2026

Stock Comparison

AstraZeneca PLC vs AutoZone, Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

AstraZeneca PLC

AZN · London Stock Exchange

Market cap (USD)
Gross margin (TTM)
Operating margin (TTM)
Net margin (TTM)
SectorHealthcare
Industry
CountryGB
Data as of2026-01-02
Moat score
71/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into AstraZeneca PLC's moat claims, evidence, and risks.

View AZN analysis

AutoZone, Inc.

AZO · New York Stock Exchange

Market cap (USD)$55.7B
Gross margin (TTM)52.2%
Operating margin (TTM)18.4%
Net margin (TTM)12.8%
SectorConsumer
IndustryAuto - Parts
CountryUS
Data as of2025-12-31
Moat score
59/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into AutoZone, Inc.'s moat claims, evidence, and risks.

View AZO analysis

Comparison highlights

  • Moat score gap: AstraZeneca PLC leads (71 / 100 vs 59 / 100 for AutoZone, Inc.).
  • Segment focus: AstraZeneca PLC has 6 segments (41% in Oncology); AutoZone, Inc. has 2 segments (88% in U.S. Auto Parts Retail & Commercial Distribution).
  • Primary market structure: Oligopoly vs Competitive. Pricing power: Strong vs Moderate.
  • Moat breadth: AstraZeneca PLC has 4 moat types across 3 domains; AutoZone, Inc. has 6 across 3.

Primary market context

AstraZeneca PLC

Oncology

Market

Innovator oncology therapeutics (branded prescription medicines)

Geography

Global

Customer

Hospitals, oncology clinics, payers

Role

Innovator biopharmaceutical company

Revenue share

41%

AutoZone, Inc.

U.S. Auto Parts Retail & Commercial Distribution

Market

U.S. automotive aftermarket replacement parts & accessories retail and commercial distribution

Geography

United States

Customer

DIY consumers; professional repair shops (DIFM)

Role

Retailer and distributor

Revenue share

88%

Side-by-side metrics

AstraZeneca PLC
AutoZone, Inc.
Ticker / Exchange
AZN - London Stock Exchange
AZO - New York Stock Exchange
Market cap (USD)
n/a
$55.7B
Gross margin (TTM)
n/a
52.2%
Operating margin (TTM)
n/a
18.4%
Net margin (TTM)
n/a
12.8%
Sector
Healthcare
Consumer
Industry
n/a
Auto - Parts
HQ country
GB
US
Primary segment
Oncology
U.S. Auto Parts Retail & Commercial Distribution
Market structure
Oligopoly
Competitive
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Strong
Moderate
Moat score
71 / 100
59 / 100
Moat domains
Legal, Supply, Demand
Supply, Demand, Financial
Last update
2026-01-02
2025-12-31

Moat coverage

Shared moat types

Brand Trust

AstraZeneca PLC strengths

Regulated Standards PipeIP Choke PointCapex Knowhow Scale

AutoZone, Inc. strengths

Distribution ControlPhysical Network DensityService Field NetworkOperational ExcellenceNegative Working Capital

Segment mix

AstraZeneca PLC segments

Full profile >

Oncology

Oligopoly

41%

Cardiovascular, Renal and Metabolism (CVRM)

Competitive

23%

Respiratory & Immunology (R&I)

Oligopoly

15%

Vaccines & Immune Therapies (V&I)

Oligopoly

3%

Rare Disease

Oligopoly

16%

Other Medicines

Competitive

2%

AutoZone, Inc. segments

Full profile >

U.S. Auto Parts Retail & Commercial Distribution

Competitive

88%

International Auto Parts Retail & Commercial Distribution (Mexico & Brazil)

Competitive

12%

Want the full wide moat stocks list?

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.