VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Saturday, January 3, 2026

Stock Comparison

AstraZeneca PLC vs NIKE, Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

AstraZeneca PLC

AZN · London Stock Exchange

Market cap (USD)
Gross margin (TTM)
Operating margin (TTM)
Net margin (TTM)
SectorHealthcare
Industry
CountryGB
Data as of2026-01-02
Moat score
71/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into AstraZeneca PLC's moat claims, evidence, and risks.

View AZN analysis

NIKE, Inc.

NKE · New York Stock Exchange

Market cap (USD)$93.4B
Gross margin (TTM)41.1%
Operating margin (TTM)6.5%
Net margin (TTM)5.4%
SectorConsumer
IndustryApparel - Footwear & Accessories
CountryUS
Data as of2025-12-23
Moat score
70/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into NIKE, Inc.'s moat claims, evidence, and risks.

View NKE analysis

Comparison highlights

  • Moat score gap: AstraZeneca PLC leads (71 / 100 vs 70 / 100 for NIKE, Inc.).
  • Segment focus: AstraZeneca PLC has 6 segments (41% in Oncology); NIKE, Inc. has 3 segments (57.8% in Wholesale).
  • Primary market structure: Oligopoly vs Competitive. Pricing power: Strong vs Moderate.
  • Moat breadth: AstraZeneca PLC has 4 moat types across 3 domains; NIKE, Inc. has 6 across 4.

Primary market context

AstraZeneca PLC

Oncology

Market

Innovator oncology therapeutics (branded prescription medicines)

Geography

Global

Customer

Hospitals, oncology clinics, payers

Role

Innovator biopharmaceutical company

Revenue share

41%

NIKE, Inc.

Wholesale

Market

Branded athletic & casual footwear/apparel wholesale distribution

Geography

Global

Customer

Retailers, distributors, licensees

Role

Brand owner / wholesaler

Revenue share

57.8%

Side-by-side metrics

AstraZeneca PLC
NIKE, Inc.
Ticker / Exchange
AZN - London Stock Exchange
NKE - New York Stock Exchange
Market cap (USD)
n/a
$93.4B
Gross margin (TTM)
n/a
41.1%
Operating margin (TTM)
n/a
6.5%
Net margin (TTM)
n/a
5.4%
Sector
Healthcare
Consumer
Industry
n/a
Apparel - Footwear & Accessories
HQ country
GB
US
Primary segment
Oncology
Wholesale
Market structure
Oligopoly
Competitive
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Strong
Moderate
Moat score
71 / 100
70 / 100
Moat domains
Legal, Supply, Demand
Demand, Supply, Network, Legal
Last update
2026-01-02
2025-12-23

Moat coverage

Shared moat types

IP Choke PointBrand Trust

AstraZeneca PLC strengths

Regulated Standards PipeCapex Knowhow Scale

NIKE, Inc. strengths

Procurement InertiaScale Economies Unit CostDistribution ControlEcosystem Complements

Segment mix

AstraZeneca PLC segments

Full profile >

Oncology

Oligopoly

41%

Cardiovascular, Renal and Metabolism (CVRM)

Competitive

23%

Respiratory & Immunology (R&I)

Oligopoly

15%

Vaccines & Immune Therapies (V&I)

Oligopoly

3%

Rare Disease

Oligopoly

16%

Other Medicines

Competitive

2%

NIKE, Inc. segments

Full profile >

Wholesale

Competitive

57.8%

Direct to Consumer (DTC)

Competitive

42.1%

Brand licensing & other

Competitive

0.2%

Want the full wide moat stocks list?

Browse the full ranking of wide moat stocks, updated with moat scores and segment context.

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.