VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Tuesday, December 30, 2025
Stock Comparison
Pfizer Inc. vs Roche Holding AG
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
Pfizer Inc.
PFE · New York Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Roche Holding AG
ROG · SIX Swiss Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Roche Holding AG's moat claims, evidence, and risks.
View ROG analysisComparison highlights
- Moat score gap: Roche Holding AG leads (68 / 100 vs 58 / 100 for Pfizer Inc.).
- Segment focus: Pfizer Inc. has 5 segments (47.4% in Primary Care); Roche Holding AG has 2 segments (76.3% in Pharmaceuticals).
- Primary market structure: Oligopoly vs Competitive. Pricing power: Moderate vs Moderate.
- Moat breadth: Pfizer Inc. has 8 moat types across 3 domains; Roche Holding AG has 5 across 3.
Primary market context
Pfizer Inc.
Primary Care
Branded primary care medicines and vaccines (incl. cardiovascular, migraine, pneumococcal/RSV/COVID-19)
Global
Healthcare providers, payers/PBMs, pharmacies/wholesalers, and government procurement
Innovator biopharma (R&D + manufacturing + commercialization)
47.4%
Roche Holding AG
Pharmaceuticals
Innovative (branded) prescription pharmaceuticals
Global
Healthcare providers and systems (hospitals/clinics), payers/governments, and patients
Innovator pharmaceutical developer, manufacturer and marketer
76.3%
Side-by-side metrics
Moat coverage
Shared moat types
Pfizer Inc. strengths
Roche Holding AG strengths
Segment mix
Pfizer Inc. segments
Full profile >Primary Care
Oligopoly
Specialty Care
Oligopoly
Oncology
Competitive
Pfizer CentreOne
Competitive
Pfizer Ignite
Competitive
Roche Holding AG segments
Full profile >Pharmaceuticals
Competitive
Diagnostics
Oligopoly
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View the moat stocks listCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.