VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Friday, January 2, 2026
Stock Comparison
AstraZeneca PLC vs Roche Holding AG
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
AstraZeneca PLC
AZN · London Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into AstraZeneca PLC's moat claims, evidence, and risks.
View AZN analysisRoche Holding AG
ROG · SIX Swiss Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Roche Holding AG's moat claims, evidence, and risks.
View ROG analysisComparison highlights
- Moat score gap: AstraZeneca PLC leads (71 / 100 vs 68 / 100 for Roche Holding AG).
- Segment focus: AstraZeneca PLC has 6 segments (41% in Oncology); Roche Holding AG has 2 segments (76.3% in Pharmaceuticals).
- Primary market structure: Oligopoly vs Competitive. Pricing power: Strong vs Moderate.
- Moat breadth: AstraZeneca PLC has 4 moat types across 3 domains; Roche Holding AG has 5 across 3.
Primary market context
AstraZeneca PLC
Oncology
Innovator oncology therapeutics (branded prescription medicines)
Global
Hospitals, oncology clinics, payers
Innovator biopharmaceutical company
41%
Roche Holding AG
Pharmaceuticals
Innovative (branded) prescription pharmaceuticals
Global
Healthcare providers and systems (hospitals/clinics), payers/governments, and patients
Innovator pharmaceutical developer, manufacturer and marketer
76.3%
Side-by-side metrics
Moat coverage
Shared moat types
AstraZeneca PLC strengths
Roche Holding AG strengths
Segment mix
AstraZeneca PLC segments
Full profile >Oncology
Oligopoly
Cardiovascular, Renal and Metabolism (CVRM)
Competitive
Respiratory & Immunology (R&I)
Oligopoly
Vaccines & Immune Therapies (V&I)
Oligopoly
Rare Disease
Oligopoly
Other Medicines
Competitive
Roche Holding AG segments
Full profile >Pharmaceuticals
Competitive
Diagnostics
Oligopoly
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View the moat stocks listCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.