VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Wednesday, December 31, 2025
Stock Comparison
Gilead Sciences, Inc. vs The Home Depot, Inc.
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
Gilead Sciences, Inc.
GILD · NASDAQ Global Select Market
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Gilead Sciences, Inc.'s moat claims, evidence, and risks.
View GILD analysisThe Home Depot, Inc.
HD · New York Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into The Home Depot, Inc.'s moat claims, evidence, and risks.
View HD analysisComparison highlights
- Moat score gap: Gilead Sciences, Inc. leads (74 / 100 vs 69 / 100 for The Home Depot, Inc.).
- Segment focus: Gilead Sciences, Inc. has 5 segments (68.5% in HIV); The Home Depot, Inc. has 2 segments (96% in Primary segment - North American home improvement retail (stores + online)).
- Primary market structure: Oligopoly vs Competitive. Pricing power: Moderate vs Weak.
- Moat breadth: Gilead Sciences, Inc. has 8 moat types across 3 domains; The Home Depot, Inc. has 4 across 2.
Primary market context
Gilead Sciences, Inc.
HIV
HIV treatment and prevention medicines (antiretroviral therapy and PrEP)
Global (U.S. and Europe are major markets)
Patients/prescribers; reimbursed by public and private payers; distributed via wholesalers and specialty pharmacies
Drug developer and marketing authorization holder
68.5%
The Home Depot, Inc.
Primary segment - North American home improvement retail (stores + online)
Home improvement retail (omnichannel)
North America (US, Canada, Mexico)
DIY homeowners and professional contractors
Retailer
96%
Side-by-side metrics
Moat coverage
Shared moat types
No overlap yet.
Gilead Sciences, Inc. strengths
The Home Depot, Inc. strengths
Segment mix
Gilead Sciences, Inc. segments
Full profile >HIV
Oligopoly
Oncology (Cell Therapy + Trodelvy)
Oligopoly
Liver Disease
Oligopoly
Veklury (Remdesivir)
Competitive
Other Products
Competitive
The Home Depot, Inc. segments
Full profile >Primary segment - North American home improvement retail (stores + online)
Competitive
Other - Specialty trade distribution (SRS: roofing, landscape, pool)
Competitive
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View the moat stocks listCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.