VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Stock Comparison

Johnson & Johnson vs Roche Holding AG

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

Johnson & Johnson

JNJ · New York Stock Exchange

Market cap (USD)$584.4B
Gross margin (TTM)72.8%
Operating margin (TTM)27.2%
Net margin (TTM)28.5%
SectorHealthcare
IndustryDrug Manufacturers - General
CountryUS
Data as of2025-12-21
Moat score
61/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Johnson & Johnson's moat claims, evidence, and risks.

View JNJ analysis

Roche Holding AG

ROG · SIX Swiss Exchange

Market cap (USD)$292.8B
Gross margin (TTM)73.4%
Operating margin (TTM)30.8%
Net margin (TTM)17.1%
SectorHealthcare
IndustryDrug Manufacturers - General
CountryCH
Data as of2025-12-28
Moat score
68/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Roche Holding AG's moat claims, evidence, and risks.

View ROG analysis

Comparison highlights

  • Moat score gap: Roche Holding AG leads (68 / 100 vs 61 / 100 for Johnson & Johnson).
  • Segment focus: Johnson & Johnson has 2 segments (64.1% in Innovative Medicine); Roche Holding AG has 2 segments (76.3% in Pharmaceuticals).
  • Moat breadth: Johnson & Johnson has 5 moat types across 3 domains; Roche Holding AG has 5 across 3.

Primary market context

Johnson & Johnson

Innovative Medicine

Market

Branded prescription pharmaceuticals (biopharma)

Geography

Global

Customer

Wholesalers, hospitals, retailers, healthcare professionals, payers

Role

Drug discovery, development, manufacturing, commercialization

Revenue share

64.1%

Roche Holding AG

Pharmaceuticals

Market

Innovative (branded) prescription pharmaceuticals

Geography

Global

Customer

Healthcare providers and systems (hospitals/clinics), payers/governments, and patients

Role

Innovator pharmaceutical developer, manufacturer and marketer

Revenue share

76.3%

Side-by-side metrics

Johnson & Johnson
Roche Holding AG
Ticker / Exchange
JNJ - New York Stock Exchange
ROG - SIX Swiss Exchange
Market cap (USD)
$584.4B
$292.8B
Gross margin (TTM)
72.8%
73.4%
Operating margin (TTM)
27.2%
30.8%
Net margin (TTM)
28.5%
17.1%
Sector
Healthcare
Healthcare
Industry
Drug Manufacturers - General
Drug Manufacturers - General
HQ country
US
CH
Primary segment
Innovative Medicine
Pharmaceuticals
Market structure
Competitive
Competitive
Market share
n/a
n/a
HHI estimate
n/a
n/a
Pricing power
Moderate
Moderate
Moat score
61 / 100
68 / 100
Moat domains
Legal, Demand, Supply
Legal, Supply, Demand
Last update
2025-12-21
2025-12-28

Moat coverage

Shared moat types

IP Choke PointRegulated Standards Pipe

Johnson & Johnson strengths

Training Org Change CostsBrand TrustService Field Network

Roche Holding AG strengths

Capex Knowhow ScaleInstalled Base ConsumablesData Workflow Lockin

Segment mix

Johnson & Johnson segments

Full profile >

Innovative Medicine

Competitive

64.1%

MedTech

Oligopoly

35.9%

Roche Holding AG segments

Full profile >

Pharmaceuticals

Competitive

76.3%

Diagnostics

Oligopoly

23.7%

Want the full wide moat stocks list?

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Looking for expansion-stage stocks?

Proven models entering the expansion stage with unit economics that work.

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.