VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Sunday, January 11, 2026
Stock Comparison
AstraZeneca PLC vs Guidewire Software, Inc.
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
AstraZeneca PLC
AZN · London Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into AstraZeneca PLC's moat claims, evidence, and risks.
View AZN analysisGuidewire Software, Inc.
GWRE · New York Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Guidewire Software, Inc.'s moat claims, evidence, and risks.
View GWRE analysisComparison highlights
- Moat score gap: AstraZeneca PLC leads (71 / 100 vs 63 / 100 for Guidewire Software, Inc.).
- Segment focus: AstraZeneca PLC has 6 segments (41% in Oncology); Guidewire Software, Inc. has 2 segments (81.8% in Core P&C insurance platform software (InsuranceSuite, InsuranceNow, Guidewire Cloud Platform)).
- Primary market structure: Oligopoly vs Oligopoly. Pricing power: Strong vs Moderate.
- Moat breadth: AstraZeneca PLC has 4 moat types across 3 domains; Guidewire Software, Inc. has 7 across 4.
Primary market context
AstraZeneca PLC
Oncology
Innovator oncology therapeutics (branded prescription medicines)
Global
Hospitals, oncology clinics, payers
Innovator biopharmaceutical company
41%
Guidewire Software, Inc.
Core P&C insurance platform software (InsuranceSuite, InsuranceNow, Guidewire Cloud Platform)
Property & casualty insurance core systems platforms (policy administration, claims, billing) with cloud delivery
Global
Property & casualty insurers (global carriers to regional/local providers)
Vertical enterprise application vendor / cloud platform operator
81.8%
Side-by-side metrics
Moat coverage
Shared moat types
AstraZeneca PLC strengths
Guidewire Software, Inc. strengths
Segment mix
AstraZeneca PLC segments
Full profile >Oncology
Oligopoly
Cardiovascular, Renal and Metabolism (CVRM)
Competitive
Respiratory & Immunology (R&I)
Oligopoly
Vaccines & Immune Therapies (V&I)
Oligopoly
Rare Disease
Oligopoly
Other Medicines
Competitive
Guidewire Software, Inc. segments
Full profile >Core P&C insurance platform software (InsuranceSuite, InsuranceNow, Guidewire Cloud Platform)
Oligopoly
Professional services (implementation, cloud migration, integration)
Competitive
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View expansion-stage stocksCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.