VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Saturday, January 10, 2026
Stock Comparison
Berkshire Hathaway Inc. vs Vertex Pharmaceuticals Incorporated
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
Berkshire Hathaway Inc.
BRK.B · New York Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Berkshire Hathaway Inc.'s moat claims, evidence, and risks.
View BRK.B analysisVertex Pharmaceuticals Incorporated
VRTX · NASDAQ
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Vertex Pharmaceuticals Incorporated's moat claims, evidence, and risks.
View VRTX analysisComparison highlights
- Moat score gap: Vertex Pharmaceuticals Incorporated leads (99 / 100 vs 64 / 100 for Berkshire Hathaway Inc.).
- Segment focus: Berkshire Hathaway Inc. has 11 segments (28.3% in Insurance (underwriting + investment income)); Vertex Pharmaceuticals Incorporated has 3 segments (99.9% in Cystic Fibrosis CFTR Modulators).
- Primary market structure: Competitive vs Quasi-Monopoly. Pricing power: n/a vs Strong.
- Moat breadth: Berkshire Hathaway Inc. has 17 moat types across 4 domains; Vertex Pharmaceuticals Incorporated has 7 across 4.
Primary market context
Berkshire Hathaway Inc.
Insurance (underwriting + investment income)
Insurance and reinsurance (property and casualty + life/health), including float-funded investing
Global
Consumers and businesses (policyholders) and insurers (reinsurance cedents)
Underwriter and reinsurer plus investment manager of float
28.3%
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis CFTR Modulators
CFTR modulator therapies for cystic fibrosis
U.S., Europe, Australia, Canada
Patients (via specialty pharmacies/payers); CF care centers
Drug developer/manufacturer
99.9%
Side-by-side metrics
Moat coverage
Shared moat types
Berkshire Hathaway Inc. strengths
Vertex Pharmaceuticals Incorporated strengths
Segment mix
Berkshire Hathaway Inc. segments
Full profile >Insurance (underwriting + investment income)
Competitive
BNSF Railway (freight rail transportation)
Oligopoly
Berkshire Hathaway Energy (regulated utilities, pipelines, renewables)
Monopoly
Industrial products manufacturing (PCC, Lubrizol, IMC, Marmon, etc.)
Oligopoly
Building products & housing (Clayton Homes, Shaw, Johns Manville, Benjamin Moore, etc.)
Competitive
Consumer products manufacturing (Duracell, Forest River, apparel/footwear, toys, etc.)
Competitive
Service businesses (FlightSafety, NetJets, TTI, Dairy Queen, etc.)
Competitive
Retailing businesses (Berkshire Hathaway Automotive, home furnishings, jewelry, See's, etc.)
Competitive
Pilot Travel Centers (travel centers + wholesale fuel marketing)
Oligopoly
McLane (wholesale distribution to convenience stores and restaurants)
Oligopoly
Holding company capital allocation and investing
Competitive
Vertex Pharmaceuticals Incorporated segments
Full profile >Cystic Fibrosis CFTR Modulators
Quasi-Monopoly
Hemoglobinopathies Gene Therapy (CASGEVY)
Oligopoly
Acute Pain (JOURNAVX)
Competitive
Want the full wide moat stocks list?
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View the moat stocks listLooking for expansion-stage stocks?
Proven models entering the expansion stage with unit economics that work.
View expansion-stage stocksCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.