VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Saturday, January 10, 2026

Stock Comparison

Parker-Hannifin Corporation vs Vertex Pharmaceuticals Incorporated

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

Parker-Hannifin Corporation

PH · New York Stock Exchange

Market cap (USD)$117.7B
Gross margin (TTM)37.1%
Operating margin (TTM)20.8%
Net margin (TTM)18.2%
SectorIndustrials
IndustryIndustrial - Machinery
CountryUS
Data as of2025-12-31
Moat score
71/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Parker-Hannifin Corporation's moat claims, evidence, and risks.

View PH analysis

Vertex Pharmaceuticals Incorporated

VRTX · NASDAQ

Market cap (USD)$119B
Gross margin (TTM)
Operating margin (TTM)
Net margin (TTM)
SectorHealthcare
IndustryBiotechnology
CountryUS
Data as of2026-01-08
Moat score
99/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Vertex Pharmaceuticals Incorporated's moat claims, evidence, and risks.

View VRTX analysis

Comparison highlights

  • Moat score gap: Vertex Pharmaceuticals Incorporated leads (99 / 100 vs 71 / 100 for Parker-Hannifin Corporation).
  • Segment focus: Parker-Hannifin Corporation has 2 segments (68.8% in Diversified Industrial); Vertex Pharmaceuticals Incorporated has 3 segments (99.9% in Cystic Fibrosis CFTR Modulators).
  • Primary market structure: Competitive vs Quasi-Monopoly. Pricing power: Moderate vs Strong.
  • Moat breadth: Parker-Hannifin Corporation has 5 moat types across 2 domains; Vertex Pharmaceuticals Incorporated has 7 across 4.

Primary market context

Parker-Hannifin Corporation

Diversified Industrial

Market

Motion and control components & systems (industrial and mobile applications)

Geography

Global

Customer

OEMs and industrial distributors/aftermarket channels

Role

Component and system designer/manufacturer with aftermarket support

Revenue share

68.8%

Vertex Pharmaceuticals Incorporated

Cystic Fibrosis CFTR Modulators

Market

CFTR modulator therapies for cystic fibrosis

Geography

U.S., Europe, Australia, Canada

Customer

Patients (via specialty pharmacies/payers); CF care centers

Role

Drug developer/manufacturer

Revenue share

99.9%

Side-by-side metrics

Parker-Hannifin Corporation
Vertex Pharmaceuticals Incorporated
Ticker / Exchange
PH - New York Stock Exchange
VRTX - NASDAQ
Market cap (USD)
$117.7B
$119B
Gross margin (TTM)
37.1%
n/a
Operating margin (TTM)
20.8%
n/a
Net margin (TTM)
18.2%
n/a
Sector
Industrials
Healthcare
Industry
Industrial - Machinery
Biotechnology
HQ country
US
US
Primary segment
Diversified Industrial
Cystic Fibrosis CFTR Modulators
Market structure
Competitive
Quasi-Monopoly
Market share
n/a
70%-78% (reported)
HHI estimate
n/a
n/a
Pricing power
Moderate
Strong
Moat score
71 / 100
99 / 100
Moat domains
Supply, Demand
Legal, Demand, Financial, Supply
Last update
2025-12-31
2026-01-08

Moat coverage

Shared moat types

No overlap yet.

Parker-Hannifin Corporation strengths

Distribution ControlDesign In QualificationScope EconomiesOperational ExcellenceInstalled Base Consumables

Vertex Pharmaceuticals Incorporated strengths

IP Choke PointGovernment Contracting RelationshipsSwitching Costs GeneralBenchmark Pricing PowerRegulated Standards PipeService Field NetworkCapacity Moat

Segment mix

Parker-Hannifin Corporation segments

Full profile >

Diversified Industrial

Competitive

68.8%

Aerospace Systems

Oligopoly

31.2%

Vertex Pharmaceuticals Incorporated segments

Full profile >

Cystic Fibrosis CFTR Modulators

Quasi-Monopoly

99.9%

Hemoglobinopathies Gene Therapy (CASGEVY)

Oligopoly

0.1%

Acute Pain (JOURNAVX)

Competitive

n/a

Want the full wide moat stocks list?

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Proven models entering the expansion stage with unit economics that work.

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.