VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

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Sunday, January 11, 2026

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Stock Comparison

Amgen Inc. vs FedEx Corporation

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

Amgen Inc.

AMGN · Nasdaq Stock Market

Market cap (USD)$175.6B

Gross margin (TTM)66.2%

Operating margin (TTM)24.1%

Net margin (TTM)19.5%

SectorHealthcare

IndustryDrug Manufacturers - General

CountryUS

Data as of2025-12-22

Moat score

70/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Amgen Inc.'s moat claims, evidence, and risks.

View AMGN analysis

FedEx Corporation

FDX · New York Stock Exchange

Market cap (USD)—

Gross margin (TTM)—

Operating margin (TTM)—

Net margin (TTM)—

SectorIndustrials

Industry—

CountryUS

Data as of2026-01-10

Moat score

72/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into FedEx Corporation's moat claims, evidence, and risks.

View FDX analysis

Comparison highlights

Moat score gap: FedEx Corporation leads (72 / 100 vs 70 / 100 for Amgen Inc.).
Segment focus: Amgen Inc. has 3 segments (80.1% in Core Innovative Medicines); FedEx Corporation has 3 segments (85.6% in Federal Express (integrated parcel & express)).
Primary market structure: Competitive vs Oligopoly. Pricing power: Moderate vs Moderate.
Moat breadth: Amgen Inc. has 5 moat types across 3 domains; FedEx Corporation has 6 across 4.

Primary market context

Amgen Inc.

Core Innovative Medicines

Market

Branded biopharmaceutical therapies for common diseases (bone health, inflammation, oncology, cardiovascular and other specialty areas)

Geography

Global

Customer

Payers, providers, and pharmacies

Role

Drug developer/manufacturer

Revenue share

80.1%

FedEx Corporation

Federal Express (integrated parcel & express)

Market

Integrated parcel and express delivery (air-ground integrator model)

Geography

Global

Customer

Business and consumer shippers

Role

Carrier / integrator

Revenue share

85.6%

Side-by-side metrics

Amgen Inc.

FedEx Corporation

Ticker / Exchange

AMGN - Nasdaq Stock Market

FDX - New York Stock Exchange

Market cap (USD)

$175.6B

n/a

Gross margin (TTM)

66.2%

n/a

Operating margin (TTM)

24.1%

n/a

Net margin (TTM)

19.5%

n/a

Sector

Healthcare

Industrials

Industry

Drug Manufacturers - General

n/a

HQ country

Primary segment

Core Innovative Medicines

Federal Express (integrated parcel & express)

Market structure

Competitive

Oligopoly

Market share

n/a

18% (reported)

HHI estimate

n/a

2,464

Pricing power

Moderate

Moat score

70 / 100

72 / 100

Moat domains

Legal, Supply, Demand

Supply, Demand, Financial, Network

Last update

2025-12-22

2026-01-10

Moat coverage

Shared moat types

Brand Trust

Amgen Inc. strengths

IP Choke PointRegulated Standards PipeCapex Knowhow ScaleLearning Curve Yield

FedEx Corporation strengths

Physical Network DensityScale Economies Unit CostBenchmark Pricing PowerScope EconomiesData Network Effects

Segment mix

Amgen Inc. segments

Full profile >

Core Innovative Medicines

Competitive

80.1%

Rare Disease Portfolio (Horizon + others)

Quasi-Monopoly

13.3%

Biosimilars

Oligopoly

6.6%

FedEx Corporation segments

Full profile >

Federal Express (integrated parcel & express)

Oligopoly

85.6%

FedEx Freight (LTL)

Oligopoly

10.1%

Corporate, other, and eliminations (Dataworks, Office, Logistics)

Competitive

4.2%

Want the full wide moat stocks list?

Browse the full ranking of wide moat stocks, updated with moat scores and segment context.

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Looking for expansion-stage stocks?

Proven models entering the expansion stage with unit economics that work.

View expansion-stage stocks

Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.