VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Saturday, January 3, 2026
Stock Comparison
AstraZeneca PLC vs GSK plc
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
AstraZeneca PLC
AZN · London Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into AstraZeneca PLC's moat claims, evidence, and risks.
View AZN analysisGSK plc
GSK · London Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Comparison highlights
- Moat score gap: AstraZeneca PLC leads (71 / 100 vs 62 / 100 for GSK plc).
- Segment focus: AstraZeneca PLC has 6 segments (41% in Oncology); GSK plc has 3 segments (37.6% in Specialty Medicines).
- Moat breadth: AstraZeneca PLC has 4 moat types across 3 domains; GSK plc has 4 across 3.
Primary market context
AstraZeneca PLC
Oncology
Innovator oncology therapeutics (branded prescription medicines)
Global
Hospitals, oncology clinics, payers
Innovator biopharmaceutical company
41%
GSK plc
Specialty Medicines
Branded specialty pharmaceuticals (HIV, oncology, immunology/respiratory)
Global
Hospitals, specialist physicians, payers
Innovator & branded manufacturer
37.6%
Side-by-side metrics
Moat coverage
Shared moat types
AstraZeneca PLC strengths
GSK plc strengths
Segment mix
AstraZeneca PLC segments
Full profile >Oncology
Oligopoly
Cardiovascular, Renal and Metabolism (CVRM)
Competitive
Respiratory & Immunology (R&I)
Oligopoly
Vaccines & Immune Therapies (V&I)
Oligopoly
Rare Disease
Oligopoly
Other Medicines
Competitive
GSK plc segments
Full profile >Vaccines
Oligopoly
Specialty Medicines
Oligopoly
General Medicines
Competitive
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View the moat stocks listCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.