VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Saturday, January 10, 2026
Stock Comparison
Cboe Global Markets, Inc. vs Vertex Pharmaceuticals Incorporated
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
Cboe Global Markets, Inc.
CBOE · Cboe BZX
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Cboe Global Markets, Inc.'s moat claims, evidence, and risks.
View CBOE analysisVertex Pharmaceuticals Incorporated
VRTX · NASDAQ
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Vertex Pharmaceuticals Incorporated's moat claims, evidence, and risks.
View VRTX analysisComparison highlights
- Moat score gap: Vertex Pharmaceuticals Incorporated leads (99 / 100 vs 76 / 100 for Cboe Global Markets, Inc.).
- Segment focus: Cboe Global Markets, Inc. has 5 segments (60.8% in Options); Vertex Pharmaceuticals Incorporated has 3 segments (99.9% in Cystic Fibrosis CFTR Modulators).
- Primary market structure: Oligopoly vs Quasi-Monopoly. Pricing power: Moderate vs Strong.
- Moat breadth: Cboe Global Markets, Inc. has 8 moat types across 4 domains; Vertex Pharmaceuticals Incorporated has 7 across 4.
Primary market context
Cboe Global Markets, Inc.
Options
U.S. listed options exchanges (multi-listed + proprietary index options)
United States
Broker-dealers, market makers, institutional investors, retail order-flow intermediaries
Exchange operator (SRO) + derivatives listing venue + market data provider
60.8%
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis CFTR Modulators
CFTR modulator therapies for cystic fibrosis
U.S., Europe, Australia, Canada
Patients (via specialty pharmacies/payers); CF care centers
Drug developer/manufacturer
99.9%
Side-by-side metrics
Moat coverage
Shared moat types
Cboe Global Markets, Inc. strengths
Vertex Pharmaceuticals Incorporated strengths
Segment mix
Cboe Global Markets, Inc. segments
Full profile >Options
Oligopoly
North American Equities
Competitive
Europe and Asia Pacific
Oligopoly
Futures
Quasi-Monopoly
Global FX
Competitive
Vertex Pharmaceuticals Incorporated segments
Full profile >Cystic Fibrosis CFTR Modulators
Quasi-Monopoly
Hemoglobinopathies Gene Therapy (CASGEVY)
Oligopoly
Acute Pain (JOURNAVX)
Competitive
Want the full wide moat stocks list?
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View the moat stocks listLooking for expansion-stage stocks?
Proven models entering the expansion stage with unit economics that work.
View expansion-stage stocksCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.