VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Tuesday, December 30, 2025
Stock Comparison
Gilead Sciences, Inc. vs Merck & Co., Inc.
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
Gilead Sciences, Inc.
GILD · NASDAQ Global Select Market
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Gilead Sciences, Inc.'s moat claims, evidence, and risks.
View GILD analysisMerck & Co., Inc.
MRK · New York Stock Exchange
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Merck & Co., Inc.'s moat claims, evidence, and risks.
View MRK analysisComparison highlights
- Moat score gap: Gilead Sciences, Inc. leads (74 / 100 vs 71 / 100 for Merck & Co., Inc.).
- Segment focus: Gilead Sciences, Inc. has 5 segments (68.5% in HIV); Merck & Co., Inc. has 2 segments (89.5% in Pharmaceutical).
- Primary market structure: Oligopoly vs Competitive. Pricing power: Moderate vs Moderate.
- Moat breadth: Gilead Sciences, Inc. has 8 moat types across 3 domains; Merck & Co., Inc. has 5 across 3.
Primary market context
Gilead Sciences, Inc.
HIV
HIV treatment and prevention medicines (antiretroviral therapy and PrEP)
Global (U.S. and Europe are major markets)
Patients/prescribers; reimbursed by public and private payers; distributed via wholesalers and specialty pharmacies
Drug developer and marketing authorization holder
68.5%
Merck & Co., Inc.
Pharmaceutical
Branded prescription pharmaceuticals & human vaccines
Global
Wholesalers/retailers, managed care and government payers, hospitals/clinics
R&D-intensive innovator, manufacturer, and marketer
89.5%
Side-by-side metrics
Moat coverage
Shared moat types
Gilead Sciences, Inc. strengths
Merck & Co., Inc. strengths
Segment mix
Gilead Sciences, Inc. segments
Full profile >HIV
Oligopoly
Oncology (Cell Therapy + Trodelvy)
Oligopoly
Liver Disease
Oligopoly
Veklury (Remdesivir)
Competitive
Other Products
Competitive
Merck & Co., Inc. segments
Full profile >Pharmaceutical
Competitive
Animal Health
Oligopoly
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View the moat stocks listCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.