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Merck & Co., Inc. MRK

NYSEPharmaceuticalsFinancials to Jun 30, 2026 · Updated Oct 7, 2026

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MRK financials
Moat score
83
ROIC
6.0%
P/E
110.4
EV/EBIT
62.0
FCF yield
4.6%
Dividend yield
2.4%
Market cap
$350.2B

Moat ranks

Score rankTied #100 of 396
Durabilitymedium
Market structureCompetitive
Pricing powermoderate

Balance sheet

6/30/26
$BDec 31Jun 30
Cash14.66.8
Securities0.00.3
Long-term securities1.01.2
Restricted cash0.10.0
Debt49.353.9
Net cash-33.8-45.5
Equity52.641.9
Leverage
Debt / EBITDA
4.12×
Debt / equity
1.29×
Leases (12/31/25)
$1.2B
Capital
Diluted shares
2,470M
Book value / share
$16.98
Price / book
8.4×
Net cash / share
−$18.44
Market cap
$350.2B
Enterprise value
$395.7B

Per-share record

Fiscal years and TTM
Scale
$0$10$20$30'16'17'18'19'20'21'22'23'2425.93'2526.95TTM
Revenue per shareCash flow per share

Key indicators

Latest: Q2 '26
IndicatorLatestVs year agoLast 8 quarters
Revenue growth5.1%+7.0 pts
Operating margin-3.5%-35.1 pts
FCF margin27.0%+11.0 pts
Capex / revenue5.4%+0.5 pts
Keytruda sales$7.9B-1%
Gardasil sales$1.2B+4%
Winrevair sales$588M+75%
Livestock sales$1.0B+8%
Companion animal sales$734M+7%

Margins and growth from reported quarters; company KPIs as reported in results releases.

About MRK

Merck develops and sells prescription medicines, human vaccines and animal-health products. Pharmaceutical sales were $58.142 billion and Animal Health sales were $6.354 billion in 2025.

Revenue mix
Pharmaceutical 89.4%Animal Health 9.8%
  • IP Choke Point

    Keytruda patents and data exclusivity protect a large oncology franchise.

  • Scope Economies

    Merck sells medicines, vaccines and identification equipment across livestock and companion species through a global commercial network.

  • Data Workflow Lockin

    Allflex identification, traceability and monitoring tools sit inside daily herd management.

Timeline
  1. Sep 30, 2026

    Tulisokibart met the primary and key secondary endpoints in a Phase 2b hidradenitis-suppurativa trial, extending the acquired programme beyond bowel disease; approval and commercial uptake remain unproven.

  2. Sep 28, 2026

    Merck licensed SciBrunch SPR2015, an investigational oral KRAS G12D inhibitor, expanding its early oncology options without yet adding approved-product sales.

  3. Sep 25, 2026

    Merck and Daiichi Sankyo withdrew the ifinatamab deruxtecan application after FDA discussions found the data insufficient for accelerated approval; a Phase 3 trial remains the route to a future filing.

  4. Sep 24, 2026

    Remigromig met the BRUNELLO trial's vision endpoint, but higher rates of eye complications and treatment discontinuation than ranibizumab leave safety and commercial value uncertain.

  5. Sep 24, 2026

    The FDA approved Welireg plus Lenvima for previously treated advanced clear-cell kidney cancer, expanding access; the trial improved progression-free survival but did not show a significant overall-survival benefit.

Financial record

Fiscal year2016201720182019202020212022202320242025TTMTrendChange 2016–25
Per share ($)
Revenue14.2814.6015.7915.1616.3419.1923.3223.6025.2525.9326.95+6.9%/yr
Cash flow3.722.354.083.443.005.177.515.118.456.578.08+6.5%/yr
Earnings1.410.872.322.211.784.865.710.146.747.281.28+20.0%/yr
Free cash flow3.141.663.102.141.253.425.793.597.124.936.50+5.1%/yr
Capex0.580.690.981.311.741.751.731.521.331.641.58+12.3%/yr
Dividends1.841.881.932.212.452.602.762.923.093.263.36+6.6%/yr
Book value14.3812.499.9710.049.9615.0418.0914.7618.2320.9816.98+4.3%/yr
Diluted shares (M)2,7872,7482,6792,5802,5412,5382,5422,5472,5412,5072,470-1.2%/yr
Totals ($B)
Revenue39.840.142.339.141.548.759.360.164.265.066.6+5.6%/yr
Operating income4.86.08.37.35.012.517.92.419.921.26.4+17.8%/yr
Net income3.92.46.25.74.512.314.50.417.118.33.2+18.6%/yr
Free cash flow8.84.68.35.53.28.714.79.118.112.416.1+3.9%/yr
Buybacks3.44.09.14.81.30.80.01.31.35.14.2+4.5%/yr
Dividends5.15.25.25.76.26.67.07.47.88.28.3+5.3%/yr
Net cash0.9-3.8-10.0-14.4-23.0-24.6-16.5-27.7-23.0-33.8-45.5−$34.7B
Margins & returns (%)
Gross margin64.867.868.169.367.272.070.673.276.374.873.0+10.0 pts
Operating margin12.215.019.618.712.025.730.33.931.032.69.6+20.5 pts
Net margin9.86.014.714.510.925.324.50.626.728.14.8+18.2 pts
FCF margin22.011.419.614.17.717.824.815.228.219.024.1-3.0 pts
ROIC8.010.016.214.68.516.623.63.023.920.36.0+12.3 pts
Return on equity9.87.023.322.017.832.331.61.037.034.77.6+24.9 pts
R&D % of revenue25.825.823.124.932.325.122.950.828.024.345.7-1.5 pts
Stock pay % of revenue0.80.80.81.01.11.00.91.11.21.31.3+0.5 pts
Capex % of revenue4.14.76.28.610.79.17.46.45.36.35.9+2.3 pts

Change uses 2016 and 2025 only: compound annual growth for amounts, points for margins and returns, and the change in amount for net cash. A dash means no 2016 base. Trend shows the fiscal years.

TTM = four quarters to Jun 30, 2026. Per-share values use diluted weighted shares.ROIC = operating income × (1 − 16.4% tax rate, the company's own over three fiscal years excluding one-offs) ÷ (equity + debt − cash and current securities). Returns show a dash when their base is negative or under 10% of revenue. Free cash flow = operating cash flow − capex. Debt is all borrowings; net cash counts long-term securities and excludes leases.

Moat

Moat scorecard

Moat score83
Strength
Confidence
Structure
Competitive
Durability
medium
Trajectory
narrowing
Pricing power
moderate
Segments
  • Pharmaceutical89.4%
    1 claim
  • Animal Health9.8%
    2 claims

Moat claims

Applies to
Pharmaceutical
Confidence
Durability
medium
Trajectory
narrowingas of Oct 7, 2026
Why it holds

Keytruda patents and data exclusivity protect a large oncology franchise. Intravenous protection faces US biosimilar entry from December 2028. The subcutaneous Qlex formulation has separate US protection through 2043, but patients and payers can still choose cheaper intravenous alternatives. Winrevair has US data exclusivity through 2036. These are product-specific, finite rights.

Why narrowing

Keytruda and Qlex sold $8.366 billion in Q2 2026, but the intravenous compound patent expires in December 2028; $463 million of Qlex sales and $588 million of Winrevair sales show progress without yet replacing the exposed franchise.

Indicators
  • Keytruda sales$7.9B-1%
  • Gardasil sales$1.2B+4%
  • Winrevair sales$588M+75%
  • Keytruda Qlex sales$463M
Risks
  • Patent cliffs for blockbuster products (e.g., Keytruda) and accelerated generic/biosimilar uptake
  • Patent challenges / adverse court outcomes / weaker IP regimes in some markets
  • Government price-setting or reimbursement reforms compressing economics even before loss of exclusivity

Profile change log

  1. Oct 7, 2026 · business change

    Tulisokibart met the primary and key secondary endpoints in a Phase 2b hidradenitis-suppurativa trial, extending the acquired programme beyond bowel disease; approval and commercial uptake remain unproven.

  2. Oct 7, 2026 · business change

    Merck licensed SciBrunch SPR2015, an investigational oral KRAS G12D inhibitor, expanding its early oncology options without yet adding approved-product sales.

  3. Oct 7, 2026 · business change

    Merck and Daiichi Sankyo withdrew the ifinatamab deruxtecan application after FDA discussions found the data insufficient for accelerated approval; a Phase 3 trial remains the route to a future filing.

  4. Oct 7, 2026 · business change

    The FDA approved Lipfendra, the first oral PCSK9 inhibitor, giving Merck a new cholesterol-treatment launch beyond oncology.

  5. Oct 7, 2026 · business change

    Merck bought TARGAN for about $650 million, adding automated poultry identification and vaccine-delivery equipment to Animal Health.

  6. Oct 7, 2026 · business change

    Merck bought Terns for $6.8 billion, adding blood-cancer candidate MK-4208 and recording a $5.7 billion acquired-research expense.

  7. Oct 7, 2026 · business change

    Merck bought Cidara for $9.2 billion, adding influenza-prevention candidate MK-1406 and recording a $9.0 billion acquired-research expense before approval.

  8. Oct 7, 2026 · business change

    Merck spun off Organon, separating women's health, biosimilars and established brands; the remaining business became more dependent on newer medicines and oncology.

  9. Oct 7, 2026 · analyst revision

    The latest product mix, patent calendar and pipeline evidence now support a narrowing pharmaceutical IP trajectory, widening Animal Health scope, and stable but uncertain farm-workflow protection. The bull and bear cases now test replacement of Keytruda income, acquisition returns and payer access.

  10. Oct 7, 2026 · analyst revision

    FY2025 consolidated sales replace the Q2-only segment weights. Profit shares are removed because segment profit excludes human R&D and corporate costs. The Animal Health share estimate is removed because its broad market denominator does not match the segment. Industry-wide regulatory approval is removed as a separate Animal Health moat; the two portfolio and workflow claims remain.

  11. Oct 7, 2026 · business change

    The FDA approved Welireg plus Lenvima for previously treated advanced clear-cell kidney cancer, expanding access; the trial improved progression-free survival but did not show a significant overall-survival benefit.

  12. Oct 7, 2026 · business change

    Remigromig met the BRUNELLO trial's vision endpoint, but higher rates of eye complications and treatment discontinuation than ranibizumab leave safety and commercial value uncertain.

Industry & peers

Peer map

0%10%20%30%40%50%60708090100Moat scoreIndustry medianMRKBMYPFE

Hover a point for its values; click a peer to compare. Dashed lines: industry medians.

Global prescription pharmaceuticals

As of Oct 9, 2026
CompetitiveLow cyclicalityUSD 1,668B in 2025

Prescription medicines sold through retail and hospital channels at manufacturer prices worldwide, including originator brands, generics and biosimilars. Roche and CSL Vifor compete in specialty medicines, with each serving only part of this market. This broad market excludes diagnostics, medical devices and over-the-counter medicines; it is not a company-addressable revenue forecast.

  1. Eli Lilly
2025 leaders, no comparable shares · Nature Reviews Drug Discovery
StocksMoatGross m.Op. m.
MRK8373.0%9.6%
Industry median176972.9%22.1%
Sector median557661.5%17.0%
All stocks median3987652.9%19.6%

Moat medians cover every stock. Margin medians count only stocks with collected numbers and need at least three.

Drivers & risks

Demand drivers
  • Aging populations and long treatment periods support demand for cancer, immune and neurological medicines. Patient need is less sensitive to the economic cycle than discretionary spending.
  • New indications and better clinical outcomes expand treated populations; a successful launch can replace revenue lost when an older product loses exclusivity.
  • Biologics and convenient formulations can improve care and adoption, but convenience must remain valuable against new treatments.
  • Insurance coverage and healthcare access expand demand in emerging markets; reimbursement inclusion can increase volume while lowering price.
  • Growing cancer treatment options and diagnostic testing can increase eligible patients; commercial value still depends on better outcomes and reimbursement.
Risks
  • Patent expiry and biosimilar entry remove product protection. Clinical superiority can also take share before patents expire.
  • US Medicare negotiation and international reference pricing, European reimbursement reviews and Chinese tenders constrain price. Voluntary agreements can exchange tariff relief for price concessions and change the timing of launches across countries.
  • Trials, safety findings, manufacturing control failures and failed acquired drug programmes can destroy invested capital or restrict supply. Pipeline size and patents alone do not establish commercial success.
  • Higher interest rates raise acquisition and financing costs. Tariffs, local production rules and biologic manufacturing requirements increase the cash needed to launch and supply products.
  • Exchange-rate moves change reported sales and profit for global manufacturers. Merck reported Q2 2026 sales growth of 5% in USD and 4% excluding currency, while Roche's Swiss-franc reporting faced translation pressure.
  • Vaccine eligibility, uptake and public procurement can change quickly. Pfizer’s XFG-adapted Comirnaty approval covers older people and younger people with a risk condition, constraining the eligible market.

Bulls & bears

Key question · as of Oct 7, 2026

Can new medicines and the subcutaneous Keytruda formulation replace the cash income exposed to intravenous Keytruda biosimilars from 2028 without repeated expensive pipeline purchases?

Arguments

4 forFaded: weakening or settled6 against

What to watch

  1. 1Keytruda intravenous and Qlex sales reported separately
  2. 2Winrevair, Ohtuvayre and Lipfendra launch sales and payer access
  3. 3Operating cash flow after capex and cash spent on new drug programmes

Next check: October 10, 2026 AAO BRUNELLO presentation, October 26 ESMO investor event and confirmed October 29 Q3 results; check safety and new-product sales against patent and vaccine risks.

Sources: company filings and dated sources collected for Find My Moat; market cap as of Oct 6, 2026. Not investment advice.

Cite or reuse this data

Free to reuse, commercially too, with a credit link. See the data license.

Moat Score 83/100 by <a href="https://www.findmymoat.com/stocks/XNYS:MRK">Find My Moat</a> (as of September 2026)

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