VOL. XCIV, NO. 247
★ WIDE MOAT STOCKS COMPARISON ★
NO ADVICE
Saturday, January 10, 2026
Stock Comparison
Vertex Pharmaceuticals Incorporated vs Wolters Kluwer N.V.
Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.
Vertex Pharmaceuticals Incorporated
VRTX · NASDAQ
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Vertex Pharmaceuticals Incorporated's moat claims, evidence, and risks.
View VRTX analysisWolters Kluwer N.V.
WKL · Euronext Amsterdam
Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.
Full stock profile
Dive deeper into Wolters Kluwer N.V.'s moat claims, evidence, and risks.
View WKL analysisComparison highlights
- Moat score gap: Vertex Pharmaceuticals Incorporated leads (99 / 100 vs 73 / 100 for Wolters Kluwer N.V.).
- Segment focus: Vertex Pharmaceuticals Incorporated has 3 segments (99.9% in Cystic Fibrosis CFTR Modulators); Wolters Kluwer N.V. has 5 segments (26.8% in Health).
- Primary market structure: Quasi-Monopoly vs Oligopoly. Pricing power: Strong vs Strong.
- Moat breadth: Vertex Pharmaceuticals Incorporated has 7 moat types across 4 domains; Wolters Kluwer N.V. has 6 across 2.
Primary market context
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis CFTR Modulators
CFTR modulator therapies for cystic fibrosis
U.S., Europe, Australia, Canada
Patients (via specialty pharmacies/payers); CF care centers
Drug developer/manufacturer
99.9%
Wolters Kluwer N.V.
Health
Clinical decision support and clinical drug information solutions (point-of-care) for healthcare providers
Global
Hospitals/health systems, clinicians, payers, and academic institutions
Software + expert content provider
26.8%
Side-by-side metrics
Moat coverage
Shared moat types
Vertex Pharmaceuticals Incorporated strengths
Wolters Kluwer N.V. strengths
Segment mix
Vertex Pharmaceuticals Incorporated segments
Full profile >Cystic Fibrosis CFTR Modulators
Quasi-Monopoly
Hemoglobinopathies Gene Therapy (CASGEVY)
Oligopoly
Acute Pain (JOURNAVX)
Competitive
Wolters Kluwer N.V. segments
Full profile >Health
Oligopoly
Tax & Accounting
Oligopoly
Financial & Corporate Compliance
Oligopoly
Legal & Regulatory
Oligopoly
Corporate Performance & ESG
Competitive
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Proven models entering the expansion stage with unit economics that work.
View expansion-stage stocksCuration & Accuracy
This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).
Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.