VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Friday, January 2, 2026

Stock Comparison

Gilead Sciences, Inc. vs Mettler-Toledo International Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

Gilead Sciences, Inc.

GILD · NASDAQ Global Select Market

Market cap (USD)$155.6B
Gross margin (TTM)78.7%
Operating margin (TTM)36.1%
Net margin (TTM)27.9%
SectorHealthcare
CountryUS
Data as of2025-12-30
Moat score
74/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Gilead Sciences, Inc.'s moat claims, evidence, and risks.

View GILD analysis

Mettler-Toledo International Inc.

MTD · New York Stock Exchange

Market cap (USD)
Gross margin (TTM)58.4%
Operating margin (TTM)28.6%
Net margin (TTM)21.2%
SectorHealthcare
CountryUS
Data as of2026-01-01
Moat score
73/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Mettler-Toledo International Inc.'s moat claims, evidence, and risks.

View MTD analysis

Comparison highlights

  • Moat score gap: Gilead Sciences, Inc. leads (74 / 100 vs 73 / 100 for Mettler-Toledo International Inc.).
  • Segment focus: Gilead Sciences, Inc. has 5 segments (68.5% in HIV); Mettler-Toledo International Inc. has 3 segments (56% in Laboratory Products and Services).
  • Primary market structure: Oligopoly vs Oligopoly. Pricing power: Moderate vs Strong.
  • Moat breadth: Gilead Sciences, Inc. has 8 moat types across 3 domains; Mettler-Toledo International Inc. has 5 across 3.

Primary market context

Gilead Sciences, Inc.

HIV

Market

HIV treatment and prevention medicines (antiretroviral therapy and PrEP)

Geography

Global (U.S. and Europe are major markets)

Customer

Patients/prescribers; reimbursed by public and private payers; distributed via wholesalers and specialty pharmacies

Role

Drug developer and marketing authorization holder

Revenue share

68.5%

Mettler-Toledo International Inc.

Laboratory Products and Services

Market

Laboratory precision weighing (balances/scales) and adjacent lab measurement & sample-prep instruments, plus related software and services

Geography

Global

Customer

Life science, chemical, academic, and testing laboratories (end-users) via direct sales and distributors

Role

Instrument OEM / software provider / service provider

Revenue share

56%

Side-by-side metrics

Gilead Sciences, Inc.
Mettler-Toledo International Inc.
Ticker / Exchange
GILD - NASDAQ Global Select Market
MTD - New York Stock Exchange
Market cap (USD)
$155.6B
n/a
Gross margin (TTM)
78.7%
58.4%
Operating margin (TTM)
36.1%
28.6%
Net margin (TTM)
27.9%
21.2%
Sector
Healthcare
Healthcare
HQ country
US
US
Primary segment
HIV
Laboratory Products and Services
Market structure
Oligopoly
Oligopoly
Market share
50%-60% (reported)
25%-30% (estimated)
HHI estimate
n/a
2,440
Pricing power
Moderate
Strong
Moat score
74 / 100
73 / 100
Moat domains
Demand, Legal, Supply
Demand, Supply, Legal
Last update
2025-12-30
2026-01-01

Moat coverage

Shared moat types

Switching Costs GeneralService Field NetworkCompliance AdvantageBrand Trust

Gilead Sciences, Inc. strengths

Habit DefaultIP Choke PointCapex Knowhow ScaleRegulated Standards Pipe

Mettler-Toledo International Inc. strengths

Data Workflow Lockin

Segment mix

Gilead Sciences, Inc. segments

Full profile >

HIV

Oligopoly

68.5%

Oncology (Cell Therapy + Trodelvy)

Oligopoly

11.5%

Liver Disease

Oligopoly

10.6%

Veklury (Remdesivir)

Competitive

6.3%

Other Products

Competitive

3.1%

Mettler-Toledo International Inc. segments

Full profile >

Laboratory Products and Services

Oligopoly

56%

Industrial Products and Services

Competitive

39%

Food Retailing Products and Services

Competitive

5%

Want the full wide moat stocks list?

Browse the full ranking of wide moat stocks, updated with moat scores and segment context.

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.