VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Stock Comparison

Eli Lilly and Company vs Novartis AG

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

Eli Lilly and Company

LLY · New York Stock Exchange

Market cap (USD)$952.3B
Gross margin (TTM)83.8%
Operating margin (TTM)45.6%
Net margin (TTM)31.7%
SectorHealthcare
IndustryDrug Manufacturers - General
CountryUS
Data as of2026-01-08
Moat score
82/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Eli Lilly and Company's moat claims, evidence, and risks.

View LLY analysis

Novartis AG

NOVN · SIX Swiss Exchange

Market cap (USD)$241.3B
Gross margin (TTM)75.7%
Operating margin (TTM)31.2%
Net margin (TTM)24.9%
SectorHealthcare
IndustryDrug Manufacturers - General
CountryCH
Data as of2026-01-02
Moat score
65/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Novartis AG's moat claims, evidence, and risks.

View NOVN analysis

Comparison highlights

  • Moat score gap: Eli Lilly and Company leads (82 / 100 vs 65 / 100 for Novartis AG).
  • Segment focus: Eli Lilly and Company has 5 segments (65.5% in Cardiometabolic Health); Novartis AG has 5 segments (29.3% in Oncology).
  • Moat breadth: Eli Lilly and Company has 5 moat types across 3 domains; Novartis AG has 4 across 3.

Primary market context

Eli Lilly and Company

Cardiometabolic Health

Market

Cardiometabolic pharmaceuticals (diabetes, obesity, and related metabolic diseases)

Geography

Global (with U.S. as the largest market)

Customer

Patients via prescribers and payers (commercial/government)

Role

Branded drug developer/manufacturer

Revenue share

65.5%

Novartis AG

Oncology

Market

Oncology and hematology branded medicines (including targeted therapies and radioligand therapy)

Geography

Global

Customer

Oncologists and hospitals; reimbursed by payers; hospital and specialty pharmacy channels

Role

Originator developer, manufacturer, and marketer of oncology therapies

Revenue share

29.3%

Side-by-side metrics

Eli Lilly and Company
Novartis AG
Ticker / Exchange
LLY - New York Stock Exchange
NOVN - SIX Swiss Exchange
Market cap (USD)
$952.3B
$241.3B
Gross margin (TTM)
83.8%
75.7%
Operating margin (TTM)
45.6%
31.2%
Net margin (TTM)
31.7%
24.9%
Sector
Healthcare
Healthcare
Industry
Drug Manufacturers - General
Drug Manufacturers - General
HQ country
US
CH
Primary segment
Cardiometabolic Health
Oncology
Market structure
Oligopoly
Oligopoly
Market share
55%-59% (reported)
n/a
HHI estimate
n/a
n/a
Pricing power
Strong
Strong
Moat score
82 / 100
65 / 100
Moat domains
Legal, Supply, Demand
Legal, Supply, Demand
Last update
2026-01-08
2026-01-02

Moat coverage

Shared moat types

IP Choke PointRegulated Standards PipeCapex Knowhow Scale

Eli Lilly and Company strengths

Capacity MoatReputation Reviews

Novartis AG strengths

Brand Trust

Segment mix

Eli Lilly and Company segments

Full profile >

Cardiometabolic Health

Oligopoly

65.5%

Oncology

Competitive

19.4%

Immunology

Oligopoly

9.8%

Neuroscience

Competitive

3.3%

Other

Competitive

2%

Novartis AG segments

Full profile >

Cardiovascular, Renal and Metabolic

Oligopoly

17%

Immunology

Oligopoly

18.5%

Neuroscience

Oligopoly

9.4%

Oncology

Oligopoly

29.3%

Established Brands

Competitive

25.8%

Want the full wide moat stocks list?

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.