VOL. XCIV, NO. 247

★ WIDE MOAT STOCKS COMPARISON ★

NO ADVICE

Stock Comparison

DexCom, Inc. vs Gilead Sciences, Inc.

Compare moat strength, market structure, and segment coverage to understand how each company defends its edge.

DexCom, Inc.

DXCM · Nasdaq Global Select Market

Market cap (USD)$23.6B
Gross margin (TTM)60.1%
Operating margin (TTM)19.6%
Net margin (TTM)17.9%
SectorHealthcare
IndustryMedical - Devices
CountryUS
Data as of2026-04-24
Moat score
82/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into DexCom, Inc.'s moat claims, evidence, and risks.

View DXCM analysis

Gilead Sciences, Inc.

GILD · NASDAQ Global Select Market

Market cap (USD)$165.9B
Gross margin (TTM)80.8%
Operating margin (TTM)37.4%
Net margin (TTM)28.9%
SectorHealthcare
IndustryDrug Manufacturers - General
CountryUS
Data as of2025-12-30
Moat score
74/ 100

Weighted average of segment moat scores, combining moat strength, durability, confidence, market structure, pricing power, and market share.

Full stock profile

Dive deeper into Gilead Sciences, Inc.'s moat claims, evidence, and risks.

View GILD analysis

Comparison highlights

  • Moat score gap: DexCom, Inc. leads (82 / 100 vs 74 / 100 for Gilead Sciences, Inc.).
  • Segment focus: DexCom, Inc. has 1 segment (100% in Continuous glucose monitoring systems); Gilead Sciences, Inc. has 5 segments (68.5% in HIV).
  • Moat breadth: DexCom, Inc. has 5 moat types across 3 domains; Gilead Sciences, Inc. has 8 across 3.

Primary market context

DexCom, Inc.

Continuous glucose monitoring systems

Market

Global continuous glucose monitoring systems and glucose biosensing devices

Geography

Global, with FY2025 revenue 71.5% United States and 28.5% international

Customer

People with diabetes, metabolic-health users, caregivers, clinicians, payors, distributors and pharmacy channels

Role

CGM device manufacturer, disposable sensor supplier, software/data platform and distribution partner

Revenue share

100%

Gilead Sciences, Inc.

HIV

Market

HIV treatment and prevention medicines (antiretroviral therapy and PrEP)

Geography

Global (U.S. and Europe are major markets)

Customer

Patients/prescribers; reimbursed by public and private payers; distributed via wholesalers and specialty pharmacies

Role

Drug developer and marketing authorization holder

Revenue share

68.5%

Side-by-side metrics

DexCom, Inc.
Gilead Sciences, Inc.
Ticker / Exchange
DXCM - Nasdaq Global Select Market
GILD - NASDAQ Global Select Market
Market cap (USD)
$23.6B
$165.9B
Gross margin (TTM)
60.1%
80.8%
Operating margin (TTM)
19.6%
37.4%
Net margin (TTM)
17.9%
28.9%
Sector
Healthcare
Healthcare
Industry
Medical - Devices
Drug Manufacturers - General
HQ country
US
US
Primary segment
Continuous glucose monitoring systems
HIV
Market structure
Oligopoly
Oligopoly
Market share
35.1% (estimated)
50%-60% (reported)
HHI estimate
4,452
n/a
Pricing power
Moderate
Moderate
Moat score
82 / 100
74 / 100
Moat domains
Demand, Network, Legal
Demand, Legal, Supply
Last update
2026-04-24
2025-12-30

Moat coverage

Shared moat types

Regulated Standards PipeBrand Trust

DexCom, Inc. strengths

Installed Base ConsumablesEcosystem ComplementsData Workflow Lockin

Gilead Sciences, Inc. strengths

Habit DefaultSwitching Costs GeneralIP Choke PointService Field NetworkCapex Knowhow ScaleCompliance Advantage

Segment mix

DexCom, Inc. segments

Full profile >

Continuous glucose monitoring systems

Oligopoly

100%

Gilead Sciences, Inc. segments

Full profile >

HIV

Oligopoly

68.5%

Oncology (Cell Therapy + Trodelvy)

Oligopoly

11.5%

Liver Disease

Oligopoly

10.6%

Veklury (Remdesivir)

Competitive

6.3%

Other Products

Competitive

3.1%

Want the full wide moat stocks list?

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Looking for expansion-stage stocks?

Proven models entering the expansion stage with unit economics that work.

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Curation & Accuracy

This directory blends AI‑assisted discovery with human curation. Entries are reviewed, edited, and organized with the goal of expanding coverage and sharpening quality over time. Your feedback helps steer improvements (because no single human can capture everything all at once).

Details change. Pricing, features, and availability may be incomplete or out of date. Treat listings as a starting point and verify on the provider’s site before making decisions. If you spot an error or a gap, send a quick note and I’ll adjust.